Panthers fall to 1-4 after 37-15 loss to San Francisco 49ers
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Mayfield ruled out against Rams with high-ankle sprain
Rapid Reactions: Panthers fall to 49ers, 37-15
Report: Panthers QB Mayfield suffers high ankle sprain, likely out
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49ers news: 5 winners and 1 loser from 49ers' 37-15 rout of
